Review our publications
Circulating T-cell receptor repertoire analysis improves cancer early detection
Yilong Li, Michelle Nahas, Dennis Stephens, Kate Froburg, Emma Hintz, Devin Champagne, Amaneet Lochab, Markus Brown, Jesse Abhyankar, Jasper Braun, Michelle Dinh, María Antonia Fortuño, María-del-Mar Ocón, Andrea Pasquier, Inés María Luque, Christopher W. Seder, Jeffrey A. Borgia, Luis Miguel Seijo, Luis M Montuenga, Roman Yelensky
AACR Annual Meeting 2024
Quantifiable blood TCR repertoire components associate with immune aging
Jing Hu, Mingyao Pan, Brett Reid, Shelley Tworoger, Bo Li
Nature Communications, 15: 8171 (2024)
Quantifiable TCR repertoire changes in prediagnostic blood specimens among patients with high-grade ovarian cancer
Xuexin Yu, Mingyao Pan, Jianfeng Ye, Cassandra A. Hathaway, Shelley S. Tworoger, Jayanthi Lea, Bo Li
Cell Reports Medicine 5, 101612 (2024)
GIANA allows computationally-efficient TCR clustering and multi-disease repertoire classification by isometric transformation
Hongyi Zhang, Xiaowei Zhan, Bo Li
Nature Communications, 12: 4699 (2021)
De novo prediction of cancer-associated TCRs for non-invasive cancer detection
Daria Beshnova, Jianfeng Ye, Oreoluwa Onabolu, Benjamin Moon, Wenxin Zheng, Yang-Xin Fu, James Brugarolas, Jayanthi Lea, Bo Li
Science Translational Medicine, 12, Issue 557 (2020)
Investigation of antigen-specific T cell clusters in human cancers
Hongyi Zhang, Longchao Liu, Jian Zhang, Jiahui Chen, Jianfeng Ye, Sachet Shukla, Jian Qiao, Xiaowei Zhan, Catherine Wu, Yang-Xin Fu, Bo Li
Clinical Cancer Research, 26(6):1359-1371 (2020)
AutoCAT: Automated cancer-associated TCRs discovery from TCR-seq data
Christina Wong, Bo Li
Bioinformatics, 8(2):589-591 (2022)
T cell receptor convergence is an indicator of antigen-specific T cell response in cancer immunotherapies
Mingyao Pan, Bo Li
eLife, DOI:10.7554/eLife.81952 (2022)
Ultrasensitive detection of TCR hypervariable region in solid-tissue RNA-seq data
Bo Li, Taiwen Li, Binbin Wang, Ruoxu Dou, Jun S Liu and X. Shirley Liu
Nature Genetics, 49(4):482-483 (2017)
Landscape of tumor-infiltrating T cell repertoire of human cancers
Bo Li, Taiwen Li, Jean-Christophe Pignon, Binbin Wang, Jinzeng Wang, Sachet Shukla, Ruoxu Dou, Qianming Chen, F. Stephen Hodi, Toni K. Choueiri, Catherine Wu, Nir Hacohen, Sabina Signoretti, Jun S. Liu and X. Shirley Liu
Nature Genetics, 48:725–732 (2016)